Clear Peptide Calculator

NAD+ injection calculator

Units to draw for an NAD+ dose, from the mg in the vial and the mL of liquid in it.

Grey values are an example: replace them with yours.

Common vial sizes

mL

For a ready-mixed vial, the mL in it: 5 mL at 100 mg/mL is 500 mg.

Measure with
Syringe
Pen

Typical values — check your pen's dial or choose your model.

units

mL

Blank: all the mix you made, up to 3 mL.

Ozempic, Wegovy, Mounjaro and Zepbound pens give the fixed doses on their labels and are not marked in units: see the label dose charts.

For U-100 insulin syringes of 0.3, 0.5 and 1 mL and reusable U-100 pens. What you enter stays in your browser.

Draw on a U-100 syringe

Example

Enter the vial, the water you added and your dose. The units appear here.

units

for

Print and link work once the numbers are yours.

Concentration
Each unit holds
Doses in the vial
Doses in the cartridge

Units and the dose they hold

The table fills in from your vial and water, for the syringe or pen you picked.

At your concentration. The highlighted row is your dose.
UnitsmLDose

How the numbers are found

  1. Concentration is the peptide in the vial divided by the water added.
  2. The volume of one dose is the dose divided by the concentration.
  3. On a U-100 syringe or pen 100 units are 1 mL, so units are the volume in mL times 100.
  4. A pen dials whole steps of 1 or ½ unit; each shot starts with a priming shot, which comes out of the cartridge too.

With your entries

Clear Peptide Calculator

Vial
Concentration
Dose
Draw
Syringe

Mixed on ____________

NAD+ doses: injections and infusions

NAD+ is given in two ways: as a small injection under the skin or into a muscle, drawn up with an insulin syringe, or as an infusion into a vein, with the dose diluted in a bag of saline. The doses below are the ones a named source gives, with who gave them and how.

NAD+ dosage chart: each dose with its source, route and schedule.
SourceDose and routeSchedule
Empower Pharmacy, a compounding pharmacypage updated Under the skin: about 20 mg to start, raised over the next injections to about 100 mg per injection1 to 3 times a week; to keep up, 50 to 100 mg a week
NCT06919328, a registered trialplan, no results posted100 mg in 2 mL of bacteriostatic water, under the skin, into a muscle or into a veinOne injection, with pain and discomfort scored a minute after it
Grant et al., 20198 healthy men aged 30 to 55750 mg in saline, into a vein over 6 hoursOnce; the authors call it a common regimen in clinics
Reyna et al., 2026clients of a wellness clinic500 mg mixed with bacteriostatic water and diluted in 500 mL of saline, into a veinOnce a day for 4 days in a row: the “loading dose” of the compounding pharmacy that supplied it
Yu et al., 2026180 adults with heart failure, 90 on NAD+10 mg in 100 mL of 5% glucose or saline, into a vein over about 40 to 60 minutesOnce a day for 7 days, in hospital, with their usual treatment

No published human study has given NAD+ under the skin: the pharmacy’s protocol and the trial plan are the only doses under the skin found in a named source. The studies gave it into a vein. The pharmacy in the Reyna study is Empower Pharmacy, the one whose protocol heads the table.

Each injection dose in units

An infusion dose is drawn up with a larger syringe: 500 mg at 100 mg per mL is 5 mL, more than a 1 mL insulin syringe holds. An injection dose is a fraction of a mL, and the units depend on the strength of the vial.

Units for the doses under the skin in the Empower Pharmacy protocol, at 50 mg/mL (100 mg in 2 mL, as in NCT06919328), 100 mg/mL and 200 mg/mL. Over 100 units does not fit a 1 mL syringe.
Doseat 50 mg/mLat 100 mg/mLat 200 mg/mL
20 mg402010
50 mg1005025
100 mgover 10010050

The pharmacy sells NAD+ ready mixed at 100 mg per mL and 200 mg per mL. For a ready-mixed vial, enter the mg and the mL in it; for a powder vial, the mg and the water you added.

The example in the calculator. A 500 mg vial with 5 mL is 100 mg per mL. The 20 mg starting dose is 20 ÷ 100 = 0.2 mL, which is 20 units on a U-100 syringe, and the vial holds 25 such doses. At 200 mg per mL the same dose is 0.1 mL, 10 units.

Is NAD+ FDA-approved?

No. The FDA has approved no drug made of NAD+. Pharmacies compound it under section 503A, where the FDA is still evaluating it.

FDA
No approved drug: no product with NAD+ (nadide) as its ingredient is in the Drugs@FDA data files of 2026-10-27, and DailyMed holds no FDA-approved label for one.
Compounding
“Nicotinamide Adenine Dinucleotide (NAD)” and its reduced form NADH are in Category 1 of the bulk substances nominated for compounding under section 503A: substances under evaluation, for which the FDA does not intend to act against a pharmacy that compounds them under the conditions of its guidance. NAD was in Category 1 on the list of 2024-09-27 as well.
Advisory committee
Not on the agenda of the Pharmacy Compounding Advisory Committee (meetings of October and December 2024 and July 2026).
WADA
Not named on the 2026 Prohibited List or on the 2027 List. Its method M2.2 prohibits at all times infusions and injections of “more than a total of 100 mL per 12-hour period”, except those legitimately received in hospital treatment, surgery or clinical diagnostic investigations; the limit counts the volume, whatever it holds.
Trials
No trial of NAD+ by injection or infusion has posted results on ClinicalTrials.gov.

Other calculators

Questions

How many units is 100 mg of NAD+?

It depends on the strength of the vial. At 200 mg per mL it is 50 units, at 100 mg per mL 100 units, a full 1 mL syringe. At 50 mg per mL, 100 mg in 2 mL as in trial NCT06919328, it is 2 mL, more than a 1 mL syringe holds.

How much water goes into a 500 mg NAD+ vial?

The water only sets the strength: 500 mg with 5 mL is 100 mg per mL, with 2.5 mL 200 mg per mL. A 20 mg dose is then 20 or 10 units. The reconstitution calculator finds the water for the units you want per dose. A ready-mixed vial takes no water: enter its mg and mL.

Is NAD+ a peptide?

No. NAD+, nicotinamide adenine dinucleotide, is a coenzyme made of two nucleotides joined through their phosphate groups, not a chain of amino acids. The vial math is the same: the mg in the vial, the mL of liquid and the mg in each dose.

Is NAD+ FDA-approved?

No. No approved drug is made of it; pharmacies compound it under section 503A, where the FDA lists it in Category 1, under evaluation (list of 2026-05-14).

Does WADA ban NAD+?

The Prohibited List does not name it. Its rule M2.2 limits infusions and injections to a total of 100 mL in 12 hours outside hospital treatment, surgery and diagnostic investigations, whatever they contain; an infusion in a 500 mL bag is over that volume.

Sources